General Information About Zepdon
Zepdon 400mg is an antiretroviral drug that has been formulated and manufactured by Cipla Limited, an Indian multinational pharmaceutical and biotechnology company. Each tablet contains 400mg of raltegravir, which is used alone or in combination with other antiviral drug to restrict Human Immunodeficiency Virus (HIV) infections from multiplying. Raltegravir falls under the integrase strand transfer inhibitors (INSTIs) class of HIV medications and works by inhibiting the activity of enzyme integrase. This enzyme is produced by HIV to successfully integrate the viral genetic material into the DNA of the host cells for successful replication.
The dosing regimen of Zepdon varies according to the severity of the condition as well as the patient’s age.
Zepdon tablets must be swallowed whole with or without food. You can take it at the same time as any other antiretroviral medications that have been prescribed. Do not crush, split, or dissolve the tablet in water. If a dose had been missed, patients need to take it as soon as they remember unless it is time for the next dose. In that case, the missed dose should be skipped, and patients need to continue with the regular dosage schedule. Do not change your Zepdon dose unless instructed by a doctor, otherwise your treatment may not be as effective or may cause adverse effects.
Zepdon is contraindicated in patients who are allergic to Raltegravir or any of the excipients in the drug.
Besides that, patients with liver disorder, muscle disorders, phenylketonuria (PKU), or a high level of creatine kinase should not take this medication as it could exacerbate the existing conditions. A thorough medical check-up must be done before this drug can be prescribed.
Your patients might display some side effects following Zepdon administration:
- Upper respiratory tract infections with symptoms like cough;
Alternatively, patients can also experience rare side effects:
- Blood in urine;
- Stevens-Johnson syndrome;
- Hypersensitivity reactions.
Refer to product manual for a detailed list of probable side effects, as the list provided here is not exhaustive.
Patients must not drive or handle heavy machinery if they feel dizzy after taking the medication. This medication does not cure HIV infections, but merely suppresses the replication of HIV. Hence, patients with HIV must always practice safe sex by using a latex or polyurethane condom. Patients with autoimmune disorders or myopathy should use this drug with caution.
This integrase inhibiting drug has been known to interact with antacids that contain aluminum or magnesium such as Gaviscon, and Maalox. These antacids reduce the absorption of Zepdon which renders it ineffective against treating HIV infections. In addition, this drug can also interact with antibiotic Rifampicin.
Pregnancy & Lactation
Pregnant and breastfeeding patients are not recommended to take this antiretroviral drug.
Patients who have overdosed on this medication should consult a doctor immediately. Do not increase your dose without consulting your doctor.
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