What is Tavin-L?
Tavin-L is taken with other antiretroviral medications to treat HIV. Each pill contains 300mg of tenofovir disoproxil fumarate and 300mg of lamivudine. The drug must be taken with at least one other anti-HIV medication to stop HIV from progressing to AIDS.
Dosing and Administration
One tablet should be taken orally once a day.
Patients hypersensitive to tenofovir disoproxil fumarate or lamivudine should not take Tavin-L.
Tavin-L Side Effects
Common side effects include:
- peripheral neuropathy
- depressive disorders
- abdominal cramps
Rarer adverse reacts documented include:
- renal impairment or failure
- proximal tubulopathy
- fanconi syndrome
- lactic acidosis
- tubular necrosis
This med may cause other adverse effects including redistribution of body fat and decreased bone density. Let a doctor know right away if you start to feel any physical or mental differences after beginning Tavin-L.
Precautions and Warnings
Patients with a creatinine clearance less than 50 ml/min should not take Tavin-L. Exacerbations of hepatic impairment have been reported by patients co-infected with hepatitis B after discontinuing Tavin-L. Patients with HCV taking interferon alfa and ribavirin may be at an increased risk of hepatic decompensation. Co-administration of didanosine and Tavin-L is not recommended for initial anti-HIV therapy because it can render this drug ineffective in the early stages of treatment.
Concurrent use of nephrotoxic drug therapy may increase risks of renal impairment. Co-administrtion of drugs associated with pancreatitis or peripheral neuropathy such as alcohol, IV pentamidine, sulfonamides, dapsone, isoniazid, stavudine and zalcitabine should be avoided if possible or taken with precaution. Tavin-L can increase the risks of side effects associated with didanosine. Atazanavir and lopinavir/ritonavir can increase the risks of Tavil-L associated side effects. The drug should be discontinued if side effects worsen. Co-administering atazanavir without ritonavir is not recommended.
Pregnancy and Breastfeeding
Tavin-L can contaminate breast milk. Mothers with HIV are discouraged from breastfeeding due to the risk of passing the virus to the child.
No specific antidote exists for Tavin-L. In the case of overdose, seek medical attention right away for monitoring. Activated charcoal may necessary to purge the drug.
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