Odivir Kit 250mg is an antiretroviral medication that is used to effectively treat human immunodeficiency virus (HIV) infections. It is comprised of 600mg of efavirenz, 300mg of lamivudine, and 250mg of didanosine. The combination of these drugs reduces the viral load of HIV in the blood.
Your recommended dose for this treatment will be determined by your body weight. To use this medication, take 1 tablet daily on an empty stomach, or least 2 hours after a meal. Take your dose at the same time each day. Preferably, it should be taken at night to reduce any undesirable effects during waking hours. Do not split, crush, or dissolve your pills in water, as this will reduce their efficacy.
Do not use this medication if you are allergic to efavirenz, lamivudine, or didanosine. Additionally, you may not use this medication if you are currently taking allopurinol or ribavirin. This medication is not suitable for the treatment of patient who have severe hepatic impairment, severe liver disease, or impaired renal function.
When using Odivir Kit 250mg, you may experience:
- Mild skin rash;
- And the redistribution of body fat.
You may also be at risk of developing adverse reactions during treatment, such as:
- Lactic acidosis, which is characterized by muscle pain, nausea, vomiting, fatigue, difficulty breathing, fast or irregular heartbeat, and cold or numb feelings in the limbs;
- Hypersensitivity reactions, such as hives, fever, and swelling of the mouth, tongue, and face;
- And retinal changes and optic neuritis, which involve seeing flashes of light, pain in 1 or both eyes, and vision abnormalities.
Please report any adverse effects to your doctor.
Please note that if treatment is interrupted, you should stop taking all drugs to prevent the development of any resistance.
Since this drug is formulated with 3 different components, there is a higher risk of unpleasant interactions when co-administered with other medications.
- Components that interact with efavirenz:
- Antianxiety medications (e.g. midazolam and triazolam);
- Antibiotics (e.g. clarithromycin and rifampicin);
- Antihistamines (e.g. terfenadine);
- Antiretroviral agents (e.g. saquinavir and indinavir).
- Components that interact with lamivudine:
- Antibiotics (e.g. trimethoprim, sulfamethoxazole);
- Antiretroviral agents (e.g. zidovudine).
- Components that interact with didanosine:
- Antacids (e.g. aluminum hydroxide, magnesium hydroxide);
- Antibiotics (e.g. quinolones);
- Anti-gout agents (e.g. allopurinol);
- Antiviral agents (e.g. ganciclovir).
To avoid any unsafe interactions, please inform your doctor of any medications you are taking.
Pregnancy & Lactation
Efavirenz should not be prescribed to pregnant patients or those who are planning to conceive, as it could cause developmental problems. It is particularly dangerous to be used during the first trimester. It is not currently known if this drug is excreted in human breast milk. Patients should not use this medication while breastfeeding.
Follow your dosing schedule carefully, as this will help to prevent overdose. Changing your dose without instructions from your doctor may result in accidental overdosage or subtherapeutic dosage. If overdose does occur, please seek immediate medical attention.
Alternative Brand Names
The Retrodel Kit is an alternative name.
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