What is Maximune (Invirase or Fortovase)?
Maximune is an antiviral medication formulated and released by Cipla Limited, an award-winning Indian company that specializes in biotechnology and pharmaceuticals. Each drug tablet contains 500mg of saquinavir, an inhibitor of HIV-1 protease. This enzyme is responsible for dividing newly-synthesized polyproteins into individual functional proteins found in HIV-1 particles. Maximune prevents the actions of this enzyme, resulting in the formation of immature noninfectious viral particles. A pack of Maximune contains 60 tablets that must be stored in a clean, cool, and dry place.
The recommended dosage of Maximune is 2 tablets taken twice daily in combination with ritonavir (also to be taken twice daily). This drug must be taken within 2 hours of eating a meal. A missed dose must be taken as soon as you remember, unless it is already time for the next dose. In this case, patients can continue with the usual schedule and avoid taking a double dose to compensate for the missed dose.
The usage of Maximune is contraindicated in patients who are allergic to saquinavir or any of the other ingredients in the formulation. Patients with severe hepatic impairments or who are taking other medications that can interact with Maximune should not use this drug.
Maximune Side Effects
Patients may experience some commonly documented side effects, such as:
- Chest pain;
Patients may also experience more serious reactions, such as:
- Crystals in the urine;
- Liver problems
- Blood in the urine;
- Peripheral neuropathy.
This list is not exhaustive. Read the product information pamphlet carefully for detailed information on the possible side effects.
The use of Maximune must be carefully monitored in patients with the following medical conditions:
- Liver disease;
It is not known whether this medication can interact with alcohol. Speak to your health-care practitioner if you are pregnant, planning to get pregnant, or breastfeeding.
Maximune has been known to interact with some drugs, resulting in unpleasant effects.
Some of the drugs that may interact with Maximune include:
This list is not exhaustive. Read the product pamphlet carefully for detailed information on possible drug interactions.
Pregnancy & Lactation
Saquinavir is classified under Category B of the Food and Drug Administration (FDA) Pregnancy Categories, as there are currently no adequate studies involving pregnant women. This drug may be used by pregnant women only if the potential benefits justify the potential risks to the fetus. It is not yet known if saquinavir is excreted in breast milk and should only be used if the circumstances are life threatening.
If you suspect an overdose, call Poison Control or seek immediate medical attention. Do not change your dose unless it has been advised by a health-care practitioner.
Alternative Brand Names
Maximune is also known by the brand names Invirase and Fortovase.
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