General Information On Lamivir HBV
If you are experiencing chronic hepatitis B with evidence of viral replication and active liver inflammation, Lamivir HBV may be right for you. This treatment is comprised of lamivudine, which inhibits the actions of human immunodeficiency virus (HIV) and the hepatitis B virus.
Take 1 tablet of Lamivir HBV once daily. If you miss a dose, take it as soon as possible—unless it is within 2 hours of the next dose. In this case, skip the missed dose and continue with your regular schedule.
Do not use Lamivir HBV if you are allergic to lamivudine or any of its other ingredients.
While taking this medication, you may experience the following:
- And skin rash.
In certain cases, more severe side effects may occur. Please consult your doctor if any of the following are experienced:
- Muscle aches;
- Peripheral neuropathy;
- Allergic reactions.
If any of these symptoms persist, or other side effects develop, seek medical attention.
- Lamivir HBV therapy may worsen preexisting medical conditions.
- Lactic acidosis: This condition occurs when there is a build-up of lactic acid in the bloodstream, resulting in a pH level that is lower than the normal range. Cases of lactic acidosis and severe hepatomegaly with steatosis (including fatalities) are observed in patients prescribed with nucleoside analogues. If you have known liver disease, please consult a doctor before using this medication.
- Exacerbation of hepatitis: While taking this drug, you may experience the exacerbation of hepatitis. Fatal cases of worsening of hepatitis were also reported.
- Risk of HIV-1 resistance:Lamivir HBV contains a dose of lamivudine that is lower than the dose used to treat HIV infections. If you are prescribed this drug for the treatment of chronic hepatitis B but have unrecognized an HIV infection, you may be affected by HIV resistance due to subtherapeutic dosage and inappropriate monotherapy.
Lamivudine is eliminated from the body in the urine. There is a possibility of drug interaction if you take other drugs that are also excreted in this manner. Please consult a doctor prior to taking this medication to avoid any possible complications.
Medications such as valganciclovir, famciclovir, acyclovir, and ganciclovir can result in life-threatening reactions.
Pregnancy & Lactation
Currently, Lamivir HBV is labeled under category C in the FDA’s Pregnancy Categories. As such, Lamivir HBV can only be prescribed if its potential benefits justify any potential risks to the fetus. If you are pregnant, please inform your doctor before using this medication. Breastfeeding mothers should also consult doctor for information about healthy breastfeeding practices prior to using this medication.
Currently, there is no known antidote for acute lamivudine overdosage. While taking this medication, please follow the provided dosage guidelines to avoid this condition. Any overdose should be immediately reported to a medical professional, so that proper monitoring of your condition may occur. If you feel as if your medication is not working, discuss alternatives with your doctor.
Alternative Brand Names
In the US and Canada, Lamivir HBV is marketed as Epivir HBV.
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