What is Lamivir (Lamivudine)?
Lamivir is a medication used in combination with other antiretrovirals to treat HIV. Each pill is equivalent to 150mg of lamivudine. The drug must be taken as part of a regular regimen of antiretrovirals to stop HIV from progressing to AIDS; it is not effective at treating HIV when taken alone. Lamivir may also be used in the treatment of chronic hepatitis B.
Dosing & Administration
For treating HIV, patients older than 12 should take one Lamivir tablet twice a day. The medication may be taken with or without food. Younger patients and adults with renal impairment may be administered a lower dose. Patients infected with both hepatitis B and HIV may need a higher dose of Lamivir to effectively treat both conditions.
Anyone with suspected hypersensitivity to lamivudine should avoid taking Lamivir.
Lamivir Side Effects
Patients taking Lamivir have reported the following side effects:
- malaise and fatigue
- abdominal pain
- peripheral neuropathy
- severe hepatomegaly with steatosis
- pancreatitis in pediatric patients
- lipodystrophy syndrome
- lactic acidosis
Other side effects may be associated with Lamivir. Inform your doctor immediately if you notice any changes in your health after starting Lamivir.
Precautions and Warnings
Sudden discontinuation of Lamivir has been associated with exacerbation of hepatitis symptoms. Liver functions should be monitored for a minimum of four months after discontinuation of Lamivir.
Sulfamethoxazole-trimethoprim may heighten the AUC of lamivudine by up to 44 percent. Lamivir and zalcitabine should not be taken together as these medications impair the absorption of each other.
Pregnancy & Lactation
Lamivir potentially contaminates breast milk. Mothers with HIV should not breastfeed due to the risks of passing HIV to their infant.
Lamivir can be toxic when taken in large doses. Seek out medical attention immediately if you take more tablets than has been prescribed to you.
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