What is Atazor?
Atazor is an antiretroviral medication that contains 300 mg of atazanavir, a type of protease inhibitor. It works by binding to the active site of the enzyme to prevent the virus from multiplying. This drug is indicated for the treatment of HIV infections and even as a preventative treatment following potential exposure.
Atazor is meant to be used as part of a combination therapy to treat HIV infections effectively. Patients are recommended to take 1 tablet once daily orally with food. Those who had forgotten to take their dose must take it as soon as they remember unless it is already time for the next dose. In that case, skip the missed dose and continue with the regular dosing schedule. Do not duplicate your dose.
Atavor 300mg is contraindicated in patients who are allergic to atazanavir or any of the excipients in this drug.
Atazor Side Effects
Severe side effects include:
- Abdominal pain;
- Skin rash;
If these side effects are experienced, contact your doctor. Refer to the package insert for a detailed information on the possible side effects.
Caution must be exercised if you have any underlying health conditions including diabetes, heart diseases, and liver problems, as these can increase the risk of developing adverse effects. Besides that, since this drug may induce lightheadedness or dizziness, patients should exercise caution when operating heavy machinery or driving. Atazor is not a cure for HIV infections. It is a management therapy to reduce the risk of contracting AIDS; therefore, you should always practice safe sex.
Atazanavir has been known to interact with other drugs. Some examples of drugs that can interact with atazanavir include:
- Antiarrhythmic agents (e.g. amiodarone);
- Antibiotics (e.g. clarithromycin);
- Anticonvulsants (e.g. phenytoin, carbamazepine, phenobarbital);
- Antifungal agents (e.g. ketoconazole, itraconazole, voriconazole);
- Antiretroviral agents (e.g. didanosine, efavirenz);
- CYP3A substrates;
- Hormonal contraceptive agents;
- Lipid lowering agents (e.g. rosuvastatin, atorvastatin).
The list above may not be all of the possible interactions. Always refer to the package insert for detailed information on the possible drug interactions.
Pregnancy & Lactation
Atazor is classified under category B in the US Food and Drug Administration (FDA) Pregnancy Categories. Clinical research using atazanavir was done on a limited number of pregnant women. Available human and animal data found evidence that this antiretroviral does not increase the risk of major birth defects in fetus when compared to the background rate. This drug appears to be safe to use during pregnancy. On the other hand, it is not known if atazanavir is excreted through breast milk.
Patients must not take more than the prescribed dosage to avoid a possible overdose. Those who had accidentally overdosed on Atazor must seek immediate medical intervention.
Alternative Brand Names
This drug is also available internationally, including the US and Canada, under the brand name Reyataz. It also contains 300 mg of atazanavir indicated for the treatment of HIV infections.
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