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Truvada (Emtricitabine/Tenofovir): Dosage, Uses and Side Effects

Truvada (Emtricitabine/Tenofovir): Dosage, Uses and Side Effects

What is Truvada ((Emtricitabine/Tenofovir)?

Truvada is a pill containing two drugs used in combination: emtricitabine and tenofovir disproxil fumarate. The drug is approved for two different uses. First, it is indicated, in combination with other antiretroviral agents (like NNRTIs or protease inhibitors) to treat HIV infections in adults. The other usage, known as pre-exposure prophylaxis, or PrEP, is used in combination with safer sex practices to reduce the risk of acquiring HIV for high-risk patient groups.

The Truvada generic name is tenofovir. The Truvada manufacturer is Gilead Sciences, Inc.

What is this medication used for?

This medication is used for two purposes: to treat HIV in adult patients who are already infected, or to prevent HIV transmission in people who are not infected by taking it daily as a prophylactic measure. It’s not intended to be used on a day-to-day basis. Truvada should only be used as a treatment in HIV-infected patients in combination with other antiretroviral drugs.

Who should take this drug?

Truvada is suitable for patients ages seven and up who are at risk of developing HIV infection or for patients already living with HIV to treat their infection. In the latter case, Truvada must be administered alongside other medications to ensure efficacy.

How does this medication work?

Truvada contains active ingredients that prevent HIV from becoming attached to immune cells in the body, as well as preventing the replication of HIV in T-cells once a person becomes infected. In the context of prophylaxis, several large studies have shown it is very effective in preventing transmission of HIV from a partner who is infected to one who is not.

How do I take this medication?

Truvada is very easy to administer. It is taken as a single tablet, once per day, with or without food.

Truvada side effects

In several large studies, Truvada was well-tolerated. However, there are several significant side effects which should be monitored by the patient and their clinician. You should be tested for HIV every three months while taking this drug.

Common side effects

  • Diarrhea
  • Nausea
  • Vomiting

Serious side effects

  • Kidney failure
  • Lactic acidosis
  • Liver problems

Truvada dosage

Truvada is taken as a single tablet, once daily, with or without food. Dosing for each tablet is 200mg of emtricitabine and 300mg of tenofovir disoproxil fumarate.

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