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Truvada Dosage: How to Take Truvada?

You should talk to your doctor for accurate and reliable information about the exact dose of Truvada recommended for your individual treatment. Figuring out the right amounts of Truvada you should take on your own should be avoided as the dosing of Truvada depends on the type of treatment you need. For example, recommended Truvada doses for PrEP and PEP are different. In general terms, Truvada is taken alone during PrEP (Pre Exposure Prophylaxis) but need to be taken with other medications like Isentress if treating Post Exposure Prophylaxis.


Here is a table for a quick look into the general recommended doses of Truvada, although you should talk to your doctor for personalized and more accurate dosing guidelines:

Truvada Dosage

HIV Infection

HIV Pre-exposure Prophylaxis

HIV Post-exposure Prophylaxis

Hepatitis B in HIV or Resistant HBV

One 200mg/300mg tablet once a day orally
50mg Tivicay (dolutegravir) once daily or 400mg Isentress (raltegravir) twice daily

One 200mg/300mg tablet once a day orally

One 200mg/300mg tablet once a day orally
400mg Isentress (raltegravir) twice daily

One 200mg/300mg tablet once a day orally

In summary, the most common way you may have come across Truvada dosage is for its use in PrEP. So how much Truvada should you take? Talk to your doctor about the recommended 200 mg 0r 300 mg daily doses to see if this makes sense for you. For the treatment of Hepatitis B in HIV or resistant HBV doctors usually recommend one 200 mg or 300 mg tablet daily. Lastly, for the treatment of Post Exposure Prophylaxis doctors generally recommend one 200mg or 300mg tablet daily along with two 400 mg Isentress tablets daily. Talk to your doctor about the best Truvada dosing to help in your treatment.

Why is it important to stick to recommended Truvada dosage?

Strict adherence to treatment is essential for the success of antiretroviral therapies. Truvada does not work as preventive methods if not taken consistently. The fixed-dose combination regimen is convenient to take because it only requires a single dose once a day, without regard to meal times. Drug resistance may develop if a person taking Truvada for PrEP is actually HIV-positive. That’s why it’s important for the patient to test negative before initiating PrEP. Repeat screening for HIV, renal function monitoring, risk-behavior assessment, counselling, and adherence assessment must also be performed while the person is taking PrEP. Since the cost of therapy may limit access, ask your doctor for co-payment options or visit the manufacturer’s website for medication assistance program.

How to Take Truvada?

Truvada are fixed dose combination tablets that contain emtricitabine (FTC) and disoproxil fumarate (TDF). The body converts TDF to its active component tenofovir. Both drugs have inhibitory activity against the enzyme HIV reverse transcriptase. It is the only antiretroviral regimen approved by the FDA both for the treatment of existing HV infection and as preventive method prior to anticipated exposure to the virus. As a treatment, Truvada is not used alone. It requires an additional integrase inhibitor, such as dolutegravir or raltegravir, to be effective. But as PrEP, Truvada can be used alone. In fact, it is the only medication approved for PrEP use in countries like the USA, although a number of new drugs are being studied as an alternative. There are generic equivalents to Truvada for sale in other countries like India. These generic PrEP medications contain the same active ingredients than Truvada and are often cheaper.

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