Trizivir (Abacavir/Lamivudine/Zidovudine) Uses, Side Effects and Dosage

Trizivir (Abacavir/Lamivudine/Zidovudine) Uses, Side Effects and Dosage

What is Trizivir?

Trizivir (brand name) is a combination medication by the manufacturer ViiV Healthcare, and it is suitable for adults, adolescents, and children who weigh at least 88 pounds to treat HIV infection. The drug can be used on its own as a comprehensive therapy or as part of a treatment regime in combination with other anti-HIV drugs.

Trizivir contains three active ingredients: 300mg abacavir (as abacavir sulfate), 150mg lamivudine, and 300mg zidovudine. This medication is available in a generic formulation, generally called abacavir-lamivudine-zidovudine.

What is this medication used for?

Trivizir is indicated for the treatment of HIV infection in children and adults. It can be used on its own or in combination with a number of other medications to reduce the viral load. Trivizir does not prevent the transmission of HIV from an infected to an uninfected individual.

How does this medication work?

Trivizir (generic name: abacavir-lamivudine-zidovudine) prevents the replication of HIV in the T-cells of infected individuals. The three medications it contains are different types of nucleoside reverse transcription inhibitors. (NRTIs). The drug class of NRTIs prevents HIV from replicating in the bodies of infected individuals. HIV can adapt to various drugs, so a variety of medications may be required to manage HIV infection.

How to take Trizivir

Trizivir is an easy medication to administer. It is taken once a day as a tablet containing 300mg abacavir (as abacavir sulfate), 150mg lamivudine, and 300mg zidovudine. The tablet should be taken once per day, at the same time, with or without food. If a patient misses a dose, they should take it as soon as they remember, unless it is within six hours of the subsequent dose.

Trizivir side effects

In large clinical trials, Trizivir was generally well-tolerated. However, some serious side effects can occur. One of these iis lactic acidosis, a buildup of lactic acid in the blood. This condition can be potentially fatal. The drug contains 300mg abacavir; some people are allergic to this medication. Patients considering starting treatment with Trivizir should liaise closely with their healthcare professional to create a suitable treatment regime.

Common side effects

  • Nausea
  • Vomiting
  • Diarrhea

Serious side effects

  • Lactic acidosis
  • Severe allergic reactions
  • Liver problems or failure


Trivizir contains three medications: 300mg abacavir (as abacavir sulfate), 150mg lamivudine and 300mg zidovudine. It is formulated as a single tablet and should be taken once a day, at the same time each day, with or without food.

Disclaimer: Please note that the contents of this article are for informational purposes only and should not be considered medical advice. This article, and other AIDS and HIV Information articles on AIDS Drugs Online, are not written by AIDS Drugs Online or reviewed by its staff for medical validity. All views and opinions expressed by the third-party authors are not endorsed by AIDS Drugs Online or its staff. Always consult a medical professional for medical advice.


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