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What is Rescriptor (Delavirdine) Used For? Side Effetcs and Dosage

What is Rescriptor (Delavirdine) Used For? Side Effetcs and Dosage

What is Rescriptor (Delavirdine)?

Rescriptor is the brand name for the drug delavirdine, an antiretroviral (anti-HIV) medication. The delavirdine drug class is non-nucleoside reverse transcriptase inhibitors (NNRTIs), which are also referred to as non-nukes. The drug is manufactured by ViiV Healthcare, a global researcher and developer of HIV medication. This medication received Food and Drug Administration (FDA) approval in 1997.

What is this medication used for?

Rescriptor is made of delavirdine mesylate and is used to treat, not cure, HIV. Delavirdine is used in combination with other drugs to reduce viral load, or the amount of HIV in a patient’s blood. It is typically used with at least two other anti-HIV agents as part of antiretroviral therapy (ART).

How does Delavirdine drug work?

Rescriptor works by interfering with enzymes in the body. HIV-infected cells need enzymes to make copies and spread the infection. By inhibiting the activity of the enzyme called reverse transcriptase, this drug helps reduce the production of infected cells, lowering the viral load.

How to take it

Rescriptor can be taken with or without food, though if the patient has low stomach acid it should be taken with an acidic drink such as cranberry or orange juice. Delavirdine is an oral tablet, but the 100mg dose can be dissolved in water if swallowing is difficult. The higher dose 200mg tablets must not be dissolved, crushed, or chewed, but swallowed whole. If you are taking any antacid products such as Tums or Rolaids, you need to take Rescriptor either an hour before or an hour after taking these products.

Patients should always inform their doctor or pharmacist of the other medications they are taking, as Rescriptor has complex drug interactions. Rescriptor should not be taken with alprazolam (Xanax), astemizole (Hismanal), cimetidine (Tagamet), dapsone, cisapride (Prepulsid), terfenadine (Seldane), phenytoin, phenobarbital, carbamazepine (Tegretol), triazolam (Halcion), midazolam (Versed), rifampin, rifabutin (Mycobutin), ranitidine (Zantac), nizatidine (Axid), famotidine (Pepcid), and quinidine.

Rescriptor side effects

Rescriptor is known to cause some mild, temporary side effects. If you experience a severe side effect, stop taking the drug and contact your doctor immediately.

Common side effects

  • Mild skin rash
  • Nausea
  • Headache

Severe side effects

  • Allergic reaction
  • Severe skin reaction


Rescriptor is typically prescribed as a dose of 400mg taken orally three times a day. It should not be taken on its own, but in combination with at least two other anti-HIV drugs.

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